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Engineered nanoparticles with antimicrobial property
Utilizing proteomics, we identify elevated levels of Pin1 in preclinical AD (PCAD) brain [60], consistent with the notion that PCAD subjects, characterized by normal scores on tests of cognition but having AD-like pathology in brain, respond to elevated A by increasing expression of Pin1
Among these mechanisms, IgE-mediated mast cell degranulation serves as a key driver of immediate itch responses
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