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The NADPH-dependent-oxidases which are localized in the plasma membrane are in the spotlight due to their gene expression and presence of different homologs during different stress conditions (Apel and Hirt, 2 by transferring electrons from cytosolic NADPH to O 2 , which either spontaneously dismutates to H 2 O 2 or is catalyzed by SOD

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These products are then re-esterified into phospholipids by lysophosphatidylcholine acyltransferase 3 (LPCAT3), thereby affecting the transmembrane properties of PUFAs and allowing their incorporation into cell membranes and lipids [34]