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For B12, the length is the part that does the real work

Vitamin B12 is essential in the formation of red blood cells and helps in the absorption of iron in the body

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When you are giving a B12 injection subcutaneously, you pinch the fat to make sure youre only penetrating the subcutaneous tissue (or the innermost layer of skin) and pull it away from the muscle, then insert the needle

Chandys hypothesis, that the rapid onset of the repairing processes induced by B12 shots might overwhelm the system and temporarily cause a worsening in symptoms, similar to the Jarisch-Herxheimer reaction in those treated for Lyme disease