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Large-scale CRISPR-based screens have identified thousands of degron motifs, particularly at protein C-termini, regulated by Cullin-RING E3 ligase complexes such as CRL2 and CRL4

Mild itching around the injection site as it heals

Application of mesenchymal stem cell therapy for aging frailty: from mechanisms to therapeutics

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The team will now be investigating this further, hopeful that it will allow them either to repurpose the drug or to develop even better treatments