Individuals with Gastrointestinal Disorders Conditions such as Crohns disease, celiac disease, or those who have undergone weight loss surgery can affect the bodys ability to absorb B12
Indications and Usage for B-12 Compliance Injection Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see DRUG INTERACTION), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue
This makes sense given the mechanism
Protects Against Stress & Neuro-inflammation Reduces oxidative stress in the brain
Those who are more active or have a naturally faster metabolism, are likely to see greater results than those who suffer from other medical conditions