Schermer and colleagues aimed to investigate whether treatment with inhaled corticosteroid (fluticasone propionate) or oral NAC are effective in primary care patients
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6 One study of 100mg glutathione or 200mg glutathione nasally three times daily for three months did not note benefit over placebo, though, the study noted greater than typical improvement in the placebo group as well, which researchers noted may have acted as a confounding factor
Gene expression studies in murine asthma models demonstrated thymulins ability to shift immune balance away from Th2 dominance: [3] Increased IFN- expression, stimulating Th1 cells Reduced IL-13 secretion (Th2-associated mediator) Decreased eotaxin (eosinophil chemotactic factor) Lower eosinophil, neutrophil, and mononuclear cell infiltration in bronchoalveolar lavage fluid Zinc deficiency investigations show that reduced thymulin activity impairs Th1 cell proliferation while leaving Th2 function intact, resulting in measurable Th1/Th2 imbalance
(3 ) 5.4 *12 =39,2 =4 (20 ) 80 , 800 5600
