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In research models yes, because they activate the ghrelin receptor (GHS-R), and ghrelin is the physiological regulator of appetite

Tirzepatide vs semaglutide 2.4 mg in non-diabetic obesity SURMOUNT-5 direct head-to-head, -20.2% vs -13.7% at 72 weeks: Aronne NEJM 2025

- Antioxidant and Immunity Boost: Glutathione plays a critical role in oxidation-reduction reactions within the body, helping to eliminate free radicals and strengthen immunity

any perceived synergy is entirely speculative