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EPA is more effective than DHA to improve depression-like behavior, glia cell dysfunction and hippcampal apoptosis signaling in a chronic stress-induced rat model of depression

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Specifically, statin-mediated PI3K/Akt inhibition may play a role in myopathy, inducing muscle atrophy via the forkhead box class O (FOXO) activation

Mutant APP and Amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimers disease