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Cap-dependent translation In most eukaryotic mRNAs, translation relies on eukaryotic translation initiation factor 4E (eIF4E) binding to the 5 mRNA cap (a modified nucleotide), along with the ribosome and other initiation factors

Treatment with the combination according to the invention invariably yielded statistically significantly superior results as compared to the group treated with sildenafil alone in the tests reported in Tables 1- 10

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