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[125] Also starring John Goodman, Ed Helms, and Marisa Tomei, Keaton was attached for several years before the film went into production

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Liver Although the 2004 Surgeon Generals Report concludes that the relationship between smoking and liver cancer is suggestive but not causal, a meta-analysis from the World Health Organization (WHO) International Agency for Research on Cancer found an RR of 1.55 among current smokers and 1.2 among former smokers for development of liver cancer (Lee et al., 2009)

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