Barrier dysfunction is documented and accepted in conditions such as celiac disease and Crohn's disease , and the phenomenon has been studied since the 1970s
Lapina i V
The NHS symptoms list groups them into general anaemia symptoms (tiredness, breathlessness, headaches, loss of appetite, weight loss) and neurological signs (peripheral neuropathy, balance problems, depression, memory and concentration changes, sometimes mood changes or psychosis in advanced cases)
Storage & Stability Lyophilized material is most stable when stored at -20C, protected from light and moisture, where it retains activity for 24+ months under typical laboratory conditions
Glutathione itself would oxidize completely within 14 days in plain sterile water stored at refrigerator temperature