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Elevated levels of CRP are also associated with cardiovascular diseases such as endocarditis, angina pectoris, and myocardial infarction (see, and Certain pathogens have been linked to atherogenesis and the development of clinically relevant coronary atherosclerosis

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It is studied as a melanocortin receptor (MC1R/MC4R) agonist with documented anti-inflammatory activity in mucosal, epithelial, and wound-healing models

A GeneChip Rat Gene 2.0 ST array chip (Thermo Fisher Scientific) was used to perform microarray experiments as described previously 72