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Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

The roGFP-iL gene was PCR amplified (Primers are listed in Supplementary table S3) with simultaneous introduction of Xho I and EcoR I restriction sites

Zhang et al, 2001

Recent studies have shown that glutamine-derived -KG regulates the differentiation of CD4(+) T cells into Th1-type effector T cells or Treg cells via DNA methylation and lipid homeostasis 135,136