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Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Conclusion: The results indicate that some pharmacological treatments, such as acetylcholinesterase inhibitors, statins, etc., alone or combined with other therapies, could be effective in improving the cognitive symptoms of PSCI

Systemic adverse reactions are unlikely from topical administration

These elements establish a feedback loop that delays tissue repair, making it essential to precisely regulate the localized microenvironment to address multiple pathogenic mechanisms simultaneously