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This multi-organ strategy aligns with the understanding that MS is a systemic disease affecting far more than just myelin sheaths

Significance was expressed in terms of P value, which was considered significant when it was less than or equal to 0.05

Furthermore, its effects on damaged skin, muscle, tendon, and bone are comparable to those in the gastrointestinal tract (and liver, pancreas lesions) [1], kidney and cardiovascular system (particularly affecting blood vessels and vessel recruitment as part of therapy for heart failure and lung lesions, counteracting arrhythmias and thrombosis) [5,6]

Urate secretion in man: the pyrazinamide suppression test