In a study by CHEN F et al., PNMC administration decreased spindle density and increased spindle length, thereby disturbing spindle stability, and the spindle pole position of the oocyte microtubule-severing enzyme Fignl1 was weakened in oocytes exposed to PNMC, which may have led to defects in its spindle apparatus [64]
doi: 10.1128/aac.01419-22 430 VenancioA
FABPs, have high affinity for FAs, bile, and retinoids (213) and have been shown to play a role in transporting FAs between adipocytes and cancer cells in which pharmacological inhibition of FABP4 reduces TAG content in ovarian cells and aggressiveness
However, despite the good pharmacological properties shown by this molecule on several cancers, its use in the clinic is problematic because of its strong diuretic properties
It is not intended for human consumption , veterinary use, diagnostic use, therapeutic use, clinical use, injection use, or use as a food, drug, cosmetic, supplement, or household product