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When interpreted together with the findings of the STEP 4 withdrawal trial and STEP 1 off-treatment extension study, which both showed weight regain after semaglutide discontinuation (after 20 weeks treatment in STEP 4 and 68 weeks treatment in STEP 1) 23,24 , these results support the benefit of continued semaglutide treatment for sustained weight loss

Full-length growth hormone affects blood sugar regulation, stimulates IGF-1 production, causes fluid retention, and can lead to joint pain and carpal tunnel syndrome

This can be problematic for people with certain health conditions or older adults whose digestive efficiency may be compromised

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Physical changes like pale skin or a sore tongue, and digestive issues such as loss of appetite or constipation, may also be signs your body needs more B12