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They are found in three isoforms and amongst them SOD1 (Cu/Zn-SOD), a predominant oxygen radical scavenger, is localized in the cytoplasm, mitochondrial intermembrane space, nucleus, and lysosomes, whereas SOD2 (Mn-SOD) and SOD3 (Cu/Zn-SOD) are localized in the mitochondrion and extracellular matrix respectively [81, 82]

Adiponectin is associated with improvement of endothelial function after rosiglitazone treatment in non-diabetic individuals with metabolic syndrome

These blood vessels may respond well to treatment

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Testosterone is necessary for spermatogenesis and also supports male development and maturation