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Patients with NASH have increased TNF levels in both the circulation and in hepatic tissues, which correlate with disease severity and mortality 21

doi: 10.1016/j.intimp.2025.114038

These alterations in the tumor ECM induce an increase in its stiffness, typically evaluated using techniques that either require direct contact with the sample (e.g., atomic force microscopy), or measure the tumor mechanical properties in a contact-free manner (e.g., shear wave elastography, magnetic resonance elastography) (Table 3)

Sci Rep 5 , 10637 (2015)

Esta transporta los cidos grasos a la mitocondria, donde se convierte en energa a travs de procesos bioqumicos