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Description

The molecular era of the mitochondrial calcium uniporter

When NNMT activity is high, NAD+ is depleted, metabolic rate slows, and fat accumulation increases

45 CoustouV.DeleuC.SaupeS

| Dr Ben Lynch

Genetic knockout and pharmacological blockade of both Aldh1a1 and GAT1 have been reported to reduce GABAergic inhibitory post-synaptic currents (IPSCs) in striatal DA/GABA neurons (Tritsch et al., 2014