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MOTSc: Mitochondriaderived peptide with AMPK activation and insulin sensitivity effects

10.2174/1381612826666200523180301 85 PerovicD.KolencD.BilicV.SomunN.DrmicD.ElabjerE.et al (2019)

120,253 The helix-turn-helix (HTH) motif that mediates DNA-binding is located at the 3-4 segment that engages successive DNA major grooves, with a degenerate tetrapeptide sequence in 4 that enforces specificity for a particular DNA operator sequence

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Conclusion: The study concluded that interhospital referral is one of the factors contributing to the delay in presentation of ischemic stroke patients highlighting the importance of direct transport of patients from the ictus location to the acute stroke-ready hospital which would translate to a higher chance of eligibility of AIS patients to thrombolysis