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Mitochondrial functions in infection and immunity

Students designing follow-on experiments often start with these signaling maps to frame their hypotheses

An RCT in 72 patients with NAFLD found that NAC (600 mg twice daily) for 3 months significantly improved liver enzymes (ALT, AST) and markers of oxidative stress compared to control, though it did not significantly improve liver histology on biopsy (Khoshbaten et al., Hepat Mon, 2010) [33]

Natural Killer (NK) cell cytotoxicitya vital component of the innate immune system's ability to fight off viral pathogens and clear damaged cellswas elevated by up to 400% after just two weeks

1c), and by using another inhibitor of ferroptosis (deferoxamine, DFO) as a protection control (Fig