Bloating, gas, constipation, or diarrhea can also play a role in brain fog
We included studies in this meta-analysis that: (1) assessed gray matter using structural MRI, (2) reported a set of coordinates (i.e., foci) from a between-subjects contrast comparing smokers to matched nonsmoking participants, (3) reported coordinates in a defined stereotaxic space (i.e., Talairach or Montreal Neurological Institute [MNI]), (4) performed a whole-brain analysis, and (5) provided sufficient information regarding characterization of smoking behaviors (e.g., pack-years, Fagerstrm Test of Nicotine Dependence [FTND] scores, years smoking, number of cigarettes smoked per day), basic demographics of the study samples (e.g., age, sex, N ), and data analysis strategies (e.g., smoothing parameters, statistical thresholds)
It's important to start with a lower nicotine strength and gradually increase if needed
However, the evaluation improved with the change in warning photos in 2025
& Body-Malapel, M
