This result was confirmed using a cell scratch assay
The components of the plant defense system encompass physical changes in host cells, also known as constitutive defenses, such as the thickening of cell walls to stop external invaders (Martnez-Gonzlez et al., 2018
The addition of rotenone alone showed moderate growth inhibition effects on drug resistant (CHO R C5) cells, and a lesser effect on drug sensitive (AuxB1) cells
Although it is not possible to determine from this study which of the micronutrients or their combination is responsible for the observed immune reconstitution, several of the B vitamins and vitamins C and E have previously been shown to enhance cellular immunity.31,32 Supplementation of HIV-infected African women with these nutrients significantly improved CD4+, CD8+, and CD3+ cell counts, and this beneficial effect was sustained for a median of 5 years.23 Moreover, the supplement used in our study included 3 additional antioxidants (acetyl l-carnitine, N-acetyl-cysteine, and alpha lipoic acid)
Add-back therapy with norethindrone acetate is recommended to avoid serious long-term sequelae (36)
