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A common variant of IL-6R is associated with elevated IL-6 pathway activity in Alzheimers disease brains

Bourbouloux, A., Shahi, P., Chakladar, A., Delrot, S

10.1289/ehp.9932 173 PrzedborskiS.Jackson-LewisV.NainiA

Suggested causes and mechanisms include immune-mediated responses, altered drug metabolism associated with glutathione deficiency or slow acetylator phenotype, co-existing infections with cytomegalovirus (CMV) or Epstein-Barr virus (EBV), or cytokines involvement

doi:10.1039/c2pp25358e Hummel D, Lffler D, Fink G, Ternes TA (2006) Simultaneous determination of psychoactive drugs and their metabolites in aqueous matrices by liquid chromatography mass spectrometry