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(4) The study must include a certain dosage of antioxidant enzymes (e.g., SOD, catalase, glutathione peroxidase, glutathione reductase, etc.) and a certain dosage of oxidative damage markers [e.g., malondialdehyde (MDA), etc.]

This localized OS environment has been demonstrated to contribute to the abnormal proliferation of uterine leiomyoma cells by inducing dysregulation in the expression of genes associated with proliferation and apoptosis [19,20]

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Rapamycin treatment for amyotrophic lateral sclerosis: Protocol for a phase II randomized, double-blind, placebo-controlled, multicenter, clinical trial (RAP-ALS trial)