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LL-37 is also utilized via injection, though many modern dermatological protocols are exploring topical formulations for direct application to open lesions

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As can be seen from the available literature, a large number of studies using oxygen-glucose deprivation and reperfusion (OGD/R) cell cultures, as well as laboratory animal models of experimental brain ischemia mimicking conditions of ischemic injury, have demonstrated the potential benefit of neuroprotection