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More notably, citalopram treatment significantly increased the number of TdT-mediated dUTP nick end labeling (TUNEL)-positive cells, whereas melatonin and vitamin C treatment significantly attenuated citalopram-induced apoptosis

Coenzyme Q10 is a critical component of mitochondrial respiration and the reduced form (ubiquinol) plays a key role as an antioxidant, by neutralising free radicals, and first line defence against oxidative stress induced damage, within the mitochondria