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Elevated expression of asparagine synthetase (ASNS), which transfers an amide group from glutamine to aspartate for asparagine formation, is associated with resistance to asparaginase therapy in ALL (Lomelino et al., 2017)

Further, the gel formulation or composition provides controlled release of the therapeutic agent to the desired site within the auris interna for some embodiments

Prediction value of serum HBV large surface protein in different phases of HBV infection and virological response of chronic hepatitis B patients

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These results suggest that low glutathione tumor levels may be a sensitivity marker for GCLC inhibitors