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25 A larger, double-blind RCT of 243 cancer patients receiving cisplatin or oxaliplatin and diagnosed with CIPN showed no significant difference in peripheral neuropathic symptoms between oral ALA 600 mg/day orally and placebo but further studies are needed to conclusively determine if ALA could benefit this subset of patients

doi: 10.1016/j.bbrc.2021.06.036 85 YanXLiuYLiCMaoXXuTHuZet al

Product quality matters because peptide purity, sterility, labeling accuracy, and storage conditions can vary significantly

Especially during fasting, when glucose and glycogen stores are low, fatty acid oxidation (FAO) is a significant source of energy provision in the form of adenosine triphosphate (ATP)

480 IL-6 is highly expressed in the tumor microenvironment and is a major mediator of inflammation