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Injection site reactions: Mild redness, swelling, or soreness can show up

Moreover, p53 suppresses the expression of glutamine transporters and glutaminase, curbing glutamine utilization and reshaping the metabolic mercenaries to favor stress adaptation and cellular survival

The mechanism might be related to its own antioxidant properties and GSH activating effect

For motor neuron count, spinal cords from anesthetized rats were collected and post-fixed for 12 hours in 4% PFA

This might involve switching to alternative agents, modifying dosages, or implementing combination therapies specifically chosen to overcome identified resistance mechanisms [237]