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In case of Drosophila , neuronal redox balance was altered by driving CatalaseRNAi or PHGpxRNAi, along with roGFP by elav-Gal4 to deplete the respective antioxidant enzymes and express the redox biosensor

In some embodiments, the otic formulation or composition comprises about 0.03% by weight of the silicon dioxide

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Containing 0.9% benzyl alcohol, each finished batch is independently tested for sterility and supplied in a sealed 30ml borosilicate glass vial with full lot traceability