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On the other hand, because DMSO is a cell-permeable cryoprotectant and considered to exert its cryoprotective effect both intra- and extracellularly, non-cell-permeable ZIL theoretically cannot completely replace DMSO

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For instance, while quercetin has been reported to activate both enzymes, curcumin has shown potential as an activator of SIRT1, promoting its deacetylase activity and contributing to anti-inflammatory effects 178

In integrative medicine, supplements play a significant role alongside conventional treatments, and it is important to consult healthcare professionals about their use and potential interactions