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Vascular research has documented BPC-157 effects on collateral circulation following major vessel occlusion (PMID 35125818, PMID 23782145), suggesting the compound modulates vascular response under both injury and ischemic conditions

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Although Novo Nordisk has not went in to any details of side effects during trials, they did confirm that the most common adverse events with CagriSema were gastrointestinal, and the vast majority were mild to moderate and diminished over time