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A Vanquish Horizon UHPLC system coupled to a Q Exactive Plus MS (both Thermo Fisher Scientific) was used to detect glutarate or succinate

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10.4103/0971-5916.193296 Indian J

The process was pro-inflammatory as it also promoted NLRP3 activation with subsequent production of mature IL-1 and IL-18, as well as GM-CSF, although IL-6 and TNF were unaffected