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Some people notice mild side effects like redness, slight soreness, or light-headedness, but these usually fade quickly

[iv] Challenges Associated With FIH Trials Since these studies represent the first administration of an investigational drug in humans, they are associated with inherent challenges, especially safety

PMID: 40001476

Recently however, an aqueous high concentration formulation of buprenorphine has been licensed for SC administration in cats in the USA (1.8 mg/mL, Simbadol, Zoetis, Pasippany, NJ)

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