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It exhibits high copper binding affinity, influencing metalloprotein activity, collagen synthesis, and gene expression involved in tissue remodeling
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This typically manifests as increased fine lines, thinning skin, or generally worse appearance despite consistent product use
Ghrelin null mice show an increased utilization of fat as an energy substrate when placed on a high-fat diet, which may indicate that ghrelin is involved in modulating the use of metabolic substrates (349)