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For each endpoint, we permuted the exposure (Air vs

At the same time, concentrations of nicotine in these products are climbing: a 2023 study of trends in nicotine strength among e-cigarette products found that the average concentration of nicotine in e-cigarettes has increased from 2.5% to 4.4% between 2017 and 2022

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"FDA Issues Warning Letters to Manufacturers and Retailers of Illegal E-Cigarette Products." Center for Tobacco Products, www.fda.gov/tobacco-products/ctp-newsroom/fda-issues-warning-letters-manufacturers-and-retailers-illegal-e-cigarette-products.