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In calves experimentally coinfected with BRSV and Pasteurella multocida , feeding with Saccharomyces cerevisiae fermentation products (SCFP) attenuated pulmonary inflammatory responses and enhanced pulmonary plasminogen expression as well as the expression of genes involved in glutathione metabolism, indicating that gut-derived interventions can reshape systemic and pulmonary immunity 177

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IGF1R is a receptor tyrosine kinase, meaning ligand binding triggers autophosphorylation and downstream signaling cascade activation

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