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It refers to the administration of a therapeutic, prophylactic, or diagnostic substance
Possible adverse effects may include: Injection site reactions : Redness, swelling, irritation, or discomfort Gastrointestinal symptoms : Nausea, vomiting, stomach cramps, or diarrhea Headaches or dizziness Allergic reactions : Rash, itching, shortness of breath, or facial swelling (rare) Increased heart rate or anxiety (typically temporary from B-vitamins) Fatigue or weakness if used improperly Elevated liver enzymes when taken in excess particularly with methionine or choline Insomnia if taken late in the day due to increased energy levels Who should avoid or use caution
(PubMed) Sawka AM, Ray JG, Yi Q, Josse RG, Lonn E
Ethics approval and consent to participate This chart review study was approved by the Institutional Review Board (IRB) of Seoul National University Dental Hospital (#CRI15013)
Doses above ~150 mg/day arent supported by current data
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