And critically, this is a molecule your own body manufactures, declines with age, and may benefit from being supplemented biologically, that is a coherent story rather than a marketing one
Given the theoretical cancer concern (disrupting senescence surveillance) and absence of human pharmacokinetic data, caution is warranted
Its findings the safe dose range, how the compound behaves in humans, early signs of biological activity feed directly into Phase 2, where the drug is studied in patients for the first time, and therefore for the first time therapeutic efficacy is tested and the most optimal dose is investigated
38 A randomized trial of older adults found that a 16-week course of GlyNAC reduced waist circumference and improved several metabolic markers
NNMT: a bad actor in fat makes good in liver