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Mammalian lipoxygenases and their biological relevance

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*Correspondence: Bassem Sadek [email protected] This article was submitted to Neuropharmacology, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In this study, we developed an in vitro model of DR by exposing the human retinal pigment epithelial cell line (ARPE-19) to high glucose (HG) injury to test the hypothesis that the antioxidant effect of the Epitalon tetrapeptide improves the delayed healing process associated with hyperglycemia in DR

Changes in the expression of methionine adenosyltransferase genes and S-adenosylmethionine homeostasis during hepatic stellate cell activation