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Aoyagi T, Aoyama T, Kojima F, Matsuda N, Maruyama M, Hamada M et al

Instead, it contacts F324, a conserved residue in GRs and high molecular weight TrxRs involved in the recognition of the oxidized nicotinamide moiety of NADP + 53 , suggesting that 9 may interfere with NADP + release and/or with the structural changes associated with it, slowing down the oscillations between EH 2 and EH 4 during enzyme turn-over (Fig

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Dickinson, L.A., Dickinson, C.D