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Beyond just creating new enzymes, our comparative analysis uncovered previously unknown residues essential for fluorination even allowing us to rescue activity in low-performing variants

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Proc Nat Acad Sci USA

Pharmaceutics 15(4):1057 Mitoma H, Horiuchi T, Tsukamoto H, Ueda N (2018) Molecular mechanisms of action of anti-TNF- agentscomparison among therapeutic TNF- antagonists