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Patients who lose weight may notice skin changes, volume shifts, fatigue, recovery needs, inflammation concerns, or a new interest in body composition
Similarly, total oxidative status (TOS), oxidative stress index (OSI), and urinary 8-isoprostane levels (a non-enzymatic peroxidation product of arachidonic acid) tend to increase after extended or continuous NSW, with concurrent decreases or alterations in total antioxidant capacity (TAC) and total antioxidant status (TAS), highlighting an imbalance in favor of oxidative damage 74,75,76,77
Conversely, BSA-PC markedly reduced the levels of the mitochondrial fusion markers OPA1, Mitofusin-1, and Mitofusin-2 compared to BSA-treated cells (Fig 3C and 3D)
By supporting acetylcholine production, L-carnitine helps prevent neuronal aging and strengthens neuromuscular junctions