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Just taking large amounts of B12 supplements does not mean that your body will be able to use all of it

Recreational athletes can use freely

Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review

Common side effects include, but may not be limited to: pain or redness at the injection site mild diarrhea pruritus (itching) increased swelling joint pain dizziness headache nervousness or anxiety Serious side effects may include: allergic reactions peripheral vascular thrombosis hypokalemia (low potassium levels) pulmonary edema (fluid build-up around or in the lungs) thrombocytosis congestive heart failure There have been reports of anaphylactic shock and death after the parenteral administration of vitamin B12

As research compounds, they are typically available in a lyophilized powdered form, requiring reconstitution before use