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A 2025 orthopaedic sports medicine systematic review describes increasing use despite lack of FDA approval and bans in sport, and emphasizes that the evidence base is dominated by preclinical studies with limited high-quality human data

Started with 0.25 mg once daily, injecting about an inch below my elbow near where the pain was worst

However, in rare cases when a vaccine is administered improperly, a person may experience more severe symptoms, including intense shoulder pain classified as SIRVA

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