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What would change my view A well-designed randomized controlled trial directly comparing at-home microinfusion at 0.5mm with a multi-peptide serum against topical application of the same serum without the device, with VISIA or similar objective imaging at 12 and 24 weeks, would be the cleanest piece of evidence the category currently lacks

Typical program length is 46 weeks, based on provider recommendations and patient goals

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Any real effect would more plausibly be a triggered downstream cascade the peptide acting as a brief signal that sets something else in motion and the size of a trigger does not scale with effect the way a sedatives blood level does

Together, these findings suggest that the time course of presynaptic modulation ( i.e