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Red flag symptoms like sudden severe pain, numbness, weakness, fever, or changes in bladder or bowel function require immediate medical evaluation

Parenteral preparations containing benzyl alcohol should not be used in epidural or spinal anesthesia procedures

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Because research-market material is sold outside any approved supply chain, its identity and purity are unverified: published trial data describe a characterized study drug, not the contents of an arbitrary vial, so identity confirmation (for example by mass spectrometry and HPLC) and a batch certificate of analysis are the minimum a rigorous research setting should require

The authors would like to extend thanks to Steven Lee for his help in ordering and taking care of reagents for this study