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To increase the specificity of ABT263, the proteolysis-targeting chimera (PROTAC) platform was used for modification to generate three dual BCL-xL and BCL-2 inhibitors, PZ15227, 374 753b, 375 and WH244

For example, boron allows vitamin D to be more effective, and vitamin D can increase the effectiveness of resveratrol

Since smaller particles are more easily endocytosed, this suggests that the potential immunotoxicity caused by MNPs depends on intracellular processing

Wolf E, Hoeflich A, Lahm H

Endogenous ghrelin regulates episodic growth hormone (GH) secretion by amplifying GH Pulse amplitude: evidence from antagonism of the GH secretagogue-R1a receptor